Research Interest:   Biochemical Diabetology

Dr. D. Ragoobirsingh's research examines the effects of nitric oxide released from nitrosovasodilators on the plasma glucose levels and the insulin binding activity of erythrocytes and leucocytes. Organic nitrates are nitrosovasodilatory drugs used to relieve angina pectoris and myocardial ischaemia. These organic nitrates act to produce smooth muscle relaxation that results in dilation of veins, arteries and arterioles by the release of nitric oxide.

Patients on protracted treatment with these drugs may well be at risk for developing Diabetes mellitus. The findings of these investigations may well serve to protect many from the onset and complications of drug induced diabetes mellitus. In addition, his research team is also looking at food extracts used in the treatment of diabetes in folklore medicine. Efforts are being made to determine whether these actually effect changes in glucose metabolism and the possible molecular mechanisms by which they illicit their action.

Dr. Ragoobirsingh consults locally to the Diabetes Association of Jamaica and the University of the West Indies Diabetes Outreach Project; and internationally to the International Diabetes Federation, with Head Office in Brussels. All his research and professional pursuits are focused on increasing understanding of Diabetes mellitus and its complications with a view to improve the quality of care given, and ultimately the life, to diabetics